“TUBERCULOSIS – A COMMON GRANULOMATOUS DISEASE AT UNCOMMON SITES: A COMPREHENSIVE HISTOCYTOLOGICAL STUDY IN A TERTIARY CARE HOSPITAL OF CENTRAL INDIA”

Author:

Saluja Anki1,Gupta Rashmi2,Barpande Chitrangi P.3,Singh B. P.4

Affiliation:

1. PG Demonstrator, Department of Pathology, Chhattisgarh Institute of Medical Sciences, Bilaspur (Chhattisgarh).

2. Associate Professor, Department of Pathology, Chhattisgarh Institute of Medical Sciences, Bilaspur (Chhattisgarh)

3. Assistant Professor, Department of Pathology, Chhattisgarh Institute of Medical Sciences, Bilaspur (Chhattisgarh).

4. Director Professor & Head of Department, Department of Pathology, Chhattisgarh Institute of Medical Sciences, Bilaspur (Chhattisgarh).

Abstract

Background: Tuberculosis (TB) is a common granulomatous disease caused by Mycobacterium tuberculosis, which primarily affects lungs in about 80 % of cases. Extrapulmonary tuberculosis (EPTB) is dened according to WHO classication criteria as an infection by M. tuberculosis which affects tissues and organs outside the pulmonary parenchyma. Among EPTB the most common location is cervical lymphadenopathy (63- 77%). Involvement of other organs or location is extremely rare, even in countries in which tuberculosis is endemic. Aim:To study the common granulomatous lesion, tuberculosis at uncommon sites on histological and cytological preparations. Materials and methods: A retrospective study of 76 cases (presented during two years), of extrapulmonary tuberculosis excluding lung, pleura and cervical lymph nodes was undertaken. Cases were selected according to the inclusion and exclusion criteria. After morphological diagnosis, cases were subjected to modied ZN staining. This was correlated with ultrasonography and Cartridge Based Nucleic Acid Amplication Test (CBNAAT) wherever available. Results: Majority of cases (63.2%) were females. Most of the cases (28/60) belonged to the age group between 21 and 30 years. Most common of the uncommon sites were axilla followed by breast and submandibular region. Conclusions: Extrapulmonary tuberculosis is quite common and keeping a high index of suspicion helps in early diagnosis and hence early treatment of this disease.

Publisher

World Wide Journals

Reference24 articles.

1. World Health Organization. Global tuberculosis report 2018. Geneva: World Health Organization; 2018.

2. World Health Organization. Global tuberculosis report 2013. Geneva: World Health Organization; 2013.

3. World Health Organization. Global tuberculosis report 2020. Geneva: World Health Organization; 2020.

4. World Health Organization. Tuberculosis- WHO 24 March 2020. Retrieved 31 May 2020.

5. Sandhu GK. Tuberculosis: current situation, challenges and overview of its control programs in India. J Glob Infect Dis. 2011;3(2):143-150.

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