TO ASSES THE EFFICACY OF MOMETASONE AND HYDROXYPROPYLMETHYLCELLULOSE NASAL SPRAY TO CONTROL SYMPTOMS OF ALLERGIC RHINITIS: A COMPARATIVE STUDY

Abstract

Allergic rhinitis is very common disorder. It significantly effects patient's daily life. So many drugs are in use for the control of symptoms of allergic rhinitis.Steroid nasal spray was the mainstay of topical medicine for long.Hpmc powder nasal sprayis not so old medication used now a days.In our study we try to find out the effictiveness of mometasone and HPMC powder nasal spray to control the symptoms of allergic rhinitis.In each group we had 60 nos of patient receiving the medication as stated. Evaluation was done at 14th days and 28th days of starting the drugs. At day 14th The chisquare statistic was 1.8682. The p value was 0.602. The result was not significant as p more than o.5. there was same response for both drugs at 14th day of starting treatment.At day 28h The chi-square statistic was 14.8428.The p value was 0.005039.The result was significant as p less than o.5.there was same response for both drugs at 28th day of starting treatment. There was more relief of major symptoms and complete relief of symptoms with HPMC powder nasal spray at 28th day of treatment.The value of z (two proportion test ) is -3.7158 .The value of p is 0.0001.There was minimal side effects for both drugs.only 7 nos of patients said that three times daily dosage of HPMC is not convenient