CLINICO- PATHOLOGICAL STUDY OF VARIANTS OF CUTANEOUS LICHEN PLANUS

Abstract

INTRODUCTION Lichen planus is a common but, unique inammatory disorder with distinctive clinical presentation in the form of prototypic “lichenoid” papules that show peculiar colour and morphology, develop in typical locations, manifest characteristic patterns of evolution and histopathological features. The current study was aimed to study the clinical and histopathological patterns of variants of cutaneous lichen planus. The studyMETHODOLOGY was carried out in the Department of Pathology, Jhalawar medical college, Jhalawar, and the cases received in the duration of 5 years from October 2016 to October 2021 were included in the study. Patients' demographic details and clinical data in terms of duration, number, type, color, site of lesions and other associated symptoms were noted. Epidermal and dermal changes were noted on histopathology (H & E stained skin biopsies). 73 cases of lichen planus were studied and classical lichenRESULT planus was the most common variant observed. Other variants were lichen planus hypertrophicus, atrophicus, pigmentosus, follicularis, actinic and linear. Most patients were in 3rd and 4th decades of life, slight female predominance was noted. Clinically lesions were mostly pruritic with violaceous papule formation. Most patients presented within 1 to 6 months of duration and lower extremities were most common site involved. Histopathologically basal vacuolation and band like inltration were consistently seen features. Clinico- pathological correlation was seen in 95.89% cases. LichenCONCLUSION planus is a common, chronic papulosquamous disorder and with dual approach of clinical and histopathological examination, an early and precise diagnosis can be made that will help patients receive timely treatment and reduce morbidity and risk of malignant transformation.