ROLE OF LHRH ANALOGUE IN CASES OF REFRACTORY MASTALGIA.

Author:

Kumari Rinku1,Akela Ankur2,Jaiswal Pradeep3,Kr. Jha Pawan4

Affiliation:

1. Assistant Professor, Dept.Of Gen.Surgery, IGIMS, Patna.

2. Senior Resident, Dept.Of Gen.Surgery, IGIMS, Patna.

3. Additional Professor, Dept.Of Gen.Surgery, IGIMS, Patna.

4. Professor & Head of Dept.Of Gen.Surgery, IGIMS, Patna.

Abstract

Background: Mastalgia is the commonest cause of visit to the breast clinic. The present study was conducted to assess the efcacy of complete estrogen blockade (CEB) with centchroman and LHRH analog goserelin in the treatment of refractory mastalgia. Aim: To study the effect of LHRH analogue in refractory mastalgia and to increase pain free period in patients with refractory mastalgia. Methods: This is a prospective cohort study conducted in the Dept.Of Gen.Surgery IGIMS ,Patna over a period of six months.The reduction of pain score ( as measured by a visual analog scale (VAS) recorded on a breast pain chart ) to 3 or less at 6 weeks of initiation of treatment was taken as primary objective. Results: Fifty patients were enrolled in the study. The mean age of the patients was 28 years (15–45 years). The median duration of symptoms was 6 months (4–8). All of them had bilateral mastalgia. The mean pain score at start of study was 7. Conclusion: Complete estrogen blockade by means of GNRH analogue is safe and effective for treatment of refractory mastalgia.

Publisher

World Wide Journals

Subject

Visual Arts and Performing Arts,Communication,Energy Engineering and Power Technology,Renewable Energy, Sustainability and the Environment,Electrical and Electronic Engineering,Computer Science Applications,Mechanical Engineering,Transportation,Cardiology and Cardiovascular Medicine,Molecular Biology,Molecular Biology,Structural Biology,Catalysis,General Engineering,Physical and Theoretical Chemistry,Process Chemistry and Technology,Catalysis,Process Chemistry and Technology,Biochemistry,Bioengineering,Catalysis,Cell Biology,Genetics,Molecular Biology,General Medicine

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