COMPARATIVE STUDY OF DYDROGESTERONE AND NATURAL MICRONISED PROGESTERONE (NMP) IN THREATENED ABORTION

Abstract

Progesterone is also called as propregnacy hormone. Threatened abortion is bleeding that occurs during first twenty weeks of pregnancy. A major step in management includes supplementation of progesterone for continuing pregnancy. It has been suggested that some women who experience spontaneous abortion may not be producing enough progesterone, so by administrating adjuvant progesterone it may be possible to prevent miscarriage. There are several formulations. In this study ,we shall compare the efficacy of two form-the natural micronised progesterone & dydrogestrone, a synthetic form in threatened abortion. An observational study was undertaken in O & G department , JLN medical college , Bhagalpur for a period of one and half year. 50 women presented with either pain or bleeding PV within 12-20 wk of gestation. Each group of 25 given DYDR & NMP. Serum progesterone was measured at one &half month interval up to four& half months. Usg fetal weight monitored on day 0 & 135.