CYTO-HISTOLOGICAL CORRELATION OF BRONCHIAL BRUSH AND BRONCHIAL BIOPSY IN LUNG MALIGNANCIES

Abstract

BACKGROUND:Lung cancer is one of the most common cancer and cause of cancer related deaths in about 29% of males and 26% of females all over the world. Fiberoptic bronchoscopy has an excellent result in diagnosis of lung cancer when combined with brushing cytology and biopsy. The Aim of the study is to correlate AIM: cytological and histological ndings in diagnosing lung carcinomas. This study was done in Department of Pathology, Government General MATERIALS AND METHODS: and Chest Hospital, Erragada, Hyderabad, Telangana from June 2018 to May 2020. 240 clinically suspected cases of lung malignancies underwent both bronchial brush and bronchial biopsy and were included in this study.RESULTS: Out of 240 cases, malignancy was conrmed in 194 cases by histopathology of bronchial biopsy, in which 152 cases were well correlated with brush cytology. Bronchial brush cytology showed sensitivity of 78.35% , specicity of 100% and accuracy of 82.5%. Bronchial biopsy has better detection rate t CONCLUSION han bronchial brush cytology in this study. However combination of brush cytology and biopsy can be considered as the best procedures for the diagnosis of lung malignancies.