MANUAL TRACING QUANTIFICATION OF HIPPOCAMPI TO PREDICT THE LATERALIZATION OF THE SEIZURE FOCUS IN TEMPORAL LOBE EPILEPSY PATIENTS

Author:

Bansal Sofia1,Bansal Aena2,Moideen Muhuesein Tharamel3

Affiliation:

1. MD Radiology, Chettinad Hospital and Research Institute.

2. MBBS

3. MBBS MDRD, Chettinad Hospital and Research Institute

Abstract

This study was aimed to determine the ability of manual tracing quantication of hippocampi to predict the lateralization of the seizure focus in TLE patients and establish a normative data for Indian population. The study was Materials And Method: conducted in the Department of Radiology, Chettinad Hospital and Research Institute. It was a hospital based prospective double blinded study. It was approved by the human ethical committee of our institution and was performed after getting informed, written consent from all the patients referred from Neurology department of Chettinad Hospital and Research Institute, Kelambakkam. The data collection for the study was done for an 18 months' period between February 2019 and August 2020. 35 patients with clinical and EEG proven tempora Results: l lobe epilepsy patients underwent MRI brain. In 32 (91%) patients, HA was detected on quantitative volumetry as opposed to visual inspection which could detect only 26 (74%) cases out of 35. The difference was statistically signicant (p-value<0.1). The mean HV was calculated to be 2.64709 cm3 (SD - 0.0879). The mean RHV was 2.659 cm3 and the mean LHV was 2.634 cm3. Using 95% condence intervals (2SD), the upper and lower limits for HV were calculated to be 2.822 cm3 and 2.471 cm3, respectively. Mean RHV of 2.683 in males and 2.627 in females was obtained. The difference was statistically signicant (P < 0.1). The most common ndings documented in evaluation of TLE with MRI in the current Conclusion: study were hippocampal sclerosis and hippocampal atrophy

Publisher

World Wide Journals

Subject

Urology,Cardiology and Cardiovascular Medicine,Cardiology and Cardiovascular Medicine,Surgery,Small Animals,Virology,Immunology,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,Paleontology,Aquatic Science,Oceanography,Linguistics and Language,Language and Linguistics,Industrial and Manufacturing Engineering,Polymers and Plastics,Materials Science (miscellaneous)

Reference10 articles.

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