FETO-MATERNAL OUTCOME IN HELLP SYNDROME

Abstract

Background: HELLP Syndrome is a serious obstetric complication in pregnancy characterised by haemolysis, elevated liver enzymes and low platelet count. Incidence is 0.5-0.9% of all pregnancies and in 10-20% of cases with severe preeclampsia (PE) and eclampsia. Aim of the present study is to evaluate the incidence, demographic and clinical prole; and maternal and perinatal outcome in women with HELLP syndrome. Methods: All women with hypertension with 28 weeks of gestation admitted to labour room in a single unit of tertiary care hospital at Government medical College Kota, Rajasthan from January 2019 to June 2020 and fullled the inclusion criteria. Incidence of HELLP syndrome was 1.9% of total deliveries and Results: 15.3% of total HDP cases. Out of 50 cases of HELLP syndrome, 62% belonged to class III, 22% to class II and 16% to class I of Mississippi classication. Mean age of patients of HELLP syndrome in present study was 24.72 4.18 years. 32 (64%) were primigravida while 18 (36%) were gravida two or more. Mean gestational age in study group was 35.98+ -3.33 week. Maternal mortality was seen in 6 (12%) cases and most common cause attributed to MODS 4 (66.67%). Conclusions: HELLP Syndrome is a severe variant and a dreadful complication of PE and eclampsia, it needs early diagnosis which is based upon clinical and laboratory ndings and timely intervention in the form of termination of pregnancy to arrest further progress of pathophysiology leading to complications.