Affiliation:
1. M.D., (General Medicine), Assistant Professor, Department of General Medicine, Govt. Theni Medical College and Hospital, Theni- 625512.
2. M.D., DM., Assistant Professor, Department of Cardiology, Govt. Theni Medical College and Hospital
3. M.D., Assistant Professor, Department of Bio-Chemistry, Govt. Theni Medical College and Hospital
Abstract
Acute Myocardial Infarction is one of the leading causes of death worldwide with the prevalence of approximately three million people. In this
study we have investigated Biomarkers like Serum Myoglobin, Creatine kinase MB, Lactate Dehydrogenase in Acute Myocardial Infarction
within four hours and after four hours of chest pain. The possible role of Serum Myoglobin as an early indicator of Acute Myocardial Infarction. To
determine if there is signicant elevation of Serum Myoglobin less than four hours of Acute Myocardial Infarction and to compare it with other
biomarkers of Acute Myocardial Infarction. It is a case control study done among a study population of 80 patients presenting to Emergency
department of Government Theni Medical College Hospital with complains of chest pain. The study population was divided into two groups, Cases
are 40 patients with chest pain less than 4 hours of duration and Controls are 40 patients with chest pain more than 4 hours of duration. Median Age
group of patients in this study was between 51 to 60 years. Sig (2-tailed) test showed statistically signicant difference in all groups namely Serum
Myoglobin, Creatine kinase , Lactate Dehydrogenase distribution in cases and controls with p value < 0.05. According to the present ndings in our
study, the earliest Serum marker to be elevated in the case of Acute Myocardial Infarction is Serum Myoglobin.As it is not a specic marker, it can
be combined with Biomarkers like Creatine Kinase and Lactate Dehydrogenase to indentify AMI at the earliest.
Subject
General Medicine,Psychiatry and Mental health,Nutrition and Dietetics,Endocrinology, Diabetes and Metabolism,Internal Medicine,Family Practice,Psychiatry and Mental health,Public Health, Environmental and Occupational Health,Pulmonary and Respiratory Medicine,General Medicine,General Medicine,Care Planning,Public Health, Environmental and Occupational Health,Animal Science and Zoology,Nature and Landscape Conservation,Animal Science and Zoology,Ecology, Evolution, Behavior and Systematics