A STUDY ON CLINICAL PROFILE AND NON-COVID RESPIRATORY VIRAL INFECTIONS IN A NON-COVID TERTIARY CARE HOSPITAL IN KOLKATA DURING COVID PANDEMIC
Author:
Mitra Somnath1, Datta (Kanjilal) Sumana2, Datta Sukanya3, Banerjee Ahitagni3, Ghosh Purbali3, Ghoshal Arnab3
Affiliation:
1. MBBS, MD, Senior Resident, Department of Paediatric Medicine, IPGMER and SSKM Hospital, Kolkata. 2. MBBS, MD, Professor, Department of Paediatric Medicine, IPGMER and SSKM Hospital, Kolkata. 3. MBBS, MD PGT, Department of Paediatric Medicine, IPGMER and SSKM Hospital, Kolkata.
Abstract
Objectives: To evaluate the clinical picture and viral aetiologies (other than SARS-CoV-2) of acute
respiratory tract infections in under- ve children during the COVID-19 pandemic. Methods: This was a
hospital based, prospective, observational and cross-sectional study carried out among under-ve children admitted at
IPGME & R, Kolkata, satisfying both inclusion and exclusion criteria. During the study period of one and a half year, after taking
consent from the parents, clinical data were collected in pre-formed questionnaire and rt-PCR was implemented to detect
respiratory viral pathogen. The statistical analysis was done by using Statistica version 8. Results: A total of 142 children of
mean age 13.18 months with Acute Respiratory Infection (ARI) and COVID RT-PCR negative were included in this study. Passive
smoking (p-value 0.023), partially completed vaccination (p-value 0.041), non-exclusive breast-feeding in rst 6 months of life
(p-value 0.031), history of low birth weight (p-value 0.044) and family history of recent contact of ARI has statistically signicant
positive correlation with ARI (0.018). Rhinorrhoea was the most common symptom (prevalence 84%). RSV-A was the most
common viral pathogen (33.10%). The death was most strongly associated with adenovirus (RR= 7.962; OR= 28.846; 95%CI=
2.795- 297.719). Congestive cardiac failure, secondary bacterial pneumonia, acute otitis media and acute gastroenteritis were
the most prevalent complications. Conclusion: The results provided aetiology, prevalence, seasonality, and clinical
manifestations of upper respiratory tract infections and the association of complications and death with each pathogen during
the COVID-19 pandemic. Further studies will detect broader range of viruses for better clinico-virological correlation.
Publisher
World Wide Journals
Subject
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