HISTOPATHOLOGICAL STUDY OF UTERINE LEIOMYOMA IN HYSTERECTOMY SPECIMENS

Author:

Kumar Satyendra1,Jha Archana2,Mishra [Prof.] Ravi Kant3,Jana Debarshi4

Affiliation:

1. Assistant Professor, Department Of Pathology, Jawaharlal Nehru Medical College & Hospital, Bhagalpur, Bihar.

2. Associate Professor, Department Of Obstetrics And Gynaecology, Jawaharlal Nehru Medical College & Hospital, Bhagalpur, Bihar.

3. Professor And Head Of Department, Department Of Pathology, Jawaharlal Nehru Medical College & Hospital, Bhagalpur, Bihar.

4. a Young Scientist (DST), Institute Of Post-Graduate Medical Education And Research, A.J.C. Bose Road, Kolkata-700020, West Bengal, India.

Abstract

Background: Uterine leiomyoma is the most common benign neoplasm in women of reproductive age group. Hysterectomy is a mode of therapy in uterine Leiomyoma. The objective of this study was to evaluate the histopathological changes in hysterectomy specimens with uterine leiomyomas. This is a retrospective study of one hundred sixty eight patients w Methods: ho underwent hysterectomy for uterine leiomyoma. Results: Uterine leiomyoma was most common in the age group of 41-50 years (54.76%). Most common location of leiomyoma was intramural (51.2%). Degenerative changes were seen in 10.72% cases. Hyaline degeneration was the most common type of degenera-tion (7.14%). Proliferative endometrium was the most common endometrial pattern (63.1%) in uterine leiomyoma. Associated malignant lesions were observed in 1.8 % cases of uterine leiomyoma. Uterine leiomyoma is associated wi Conclusion: th degenerative changes and coexistent benign and malignant patholologies. Histopathological examination of hysterectomy specimens should be done to conrm the diagnosis and rule out other pathologies, especially malignant lesions.

Publisher

World Wide Journals

Reference17 articles.

1. Abraham J, Saldanha P. Morphological variants and secondary changes in uterine leiomyomas. Is it important to recognize them? Int J Biomed Research. 2013;4(12):254-64.

2. Ackerman, Gull B, Karlsson B, Milsom I, Granberg S. Factors associated with endometrial thickness and uterine size in random sample of postmenopausal women. Am J Obstet Gynecol 2001;185(2):386-91.

3. Begum S, Khan S. Audit of leiomyoma uterus at Khyber Teaching Hospital, Peshawar. J Ayub Med Coll 2004;16(2):46-9.

4. Chethana M, Kumar HML, Munikrishna M. Endometrial changes in uterine leiomyomas. J Clin Biomed Sci 2013;3(2):72-79.

5. Crum CP. Body of uterus and endometrium. In: Kumar V, Abbas AK, Fausto N, Eds. Robbins and Cotran Pathologic Basis of Disease. 7th ed. Philadel-phia: Saunders, 2004:1089-90.

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