LONG-COVID: AN OUTCOME OF MITOCHONDRIAL DYSFUNCTION (A BRIEF NARRATIVE REVIEW)
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Published:2022-09-01
Issue:
Volume:
Page:22-27
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ISSN:
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Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
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language:en
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Short-container-title:ijsr
Author:
Razdan Konika1, Raina Varshiesh2
Affiliation:
1. PhD, Demonstrator in Department of Microbiology, Jammu Medical College, J & K, 180004. 2. PhD, Tutor, Expert Mind IT Educational Pvt. Ltd, 109, Center Tower, Central Spine, Vidyadhar Nagar, Jaipur, Rajasthan 302039.
Abstract
A signicant proportion of patients who recovered from SARCoV-2 infection develop chronic symptoms lasting weeks or months, referred as
Long COVID. Though the exact etiology of Long COVID is unknown; however, one of major symptom experienced by these patients is chronic
fatigue syndrome which is associated with several mitochondrial disorders or viral diseases. In this review, a systematic approach has been
performed to explain Long COVID as possible outcome of mitochondrial dysfunction. The review highlights what is known in literature about the
dysfunctional pathways which can develop in mitochondria and their relationship to viruses and associated mitochondrial disorders. It also
identies potential areas which require urgent, further research in order to help clinical management and interventional studies for better long-term
outcomes.
Publisher
World Wide Journals
Subject
Physiology (medical),Ecology, Evolution, Behavior and Systematics,Physiology,General Biochemistry, Genetics and Molecular Biology,General Earth and Planetary Sciences,Pollution,General Environmental Science,Waste Management and Disposal,Artificial Intelligence,Cognitive Neuroscience,Experimental and Cognitive Psychology,Pharmacology,General Immunology and Microbiology,Applied Microbiology and Biotechnology,General Medicine,Bioengineering,Biotechnology,Cell Biology,Molecular Biology,Pharmacology (medical),Gastroenterology,Oncology,Rheumatology,Immunology and Allergy,General Biochemistry, Genetics and Molecular Biology,General Agricultural and Biological Sciences,General Earth and Planetary Sciences,General Environmental Science
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