SEVOFLURANE VERSUS PROPOFOL FOR INSERTION OF SUPRAGLOTTIC AIRWAY DEVICES – A COMPARATIVE STUDY.

Abstract

Background:-A popular method of providing anaesthesia for insertion of SGA device is with the use of bolus intravenous propofol, however it is associated with adverse effects like hypotension, apnoea, and pain on injection. Sevoflurane is a halogenated volatile anaesthetic which satisfies the conditions required for SGA devices insertion without the side effects as seen with propofol. Objective: - To compare conditions for SGA insertion following anaesthesia with inhalation of sevoflurane or intravenous injection with propofol. Methods: - 128 Patients posted for routine surgeries under general anaesthesia taken as study subject and randomly divided into 2 groups of 64 each. After premedication, Group P received intravenous propofol (2mg/kg body weight) with 100% oxygen via the face mask. In group S, Magills circuit primed with Sevoflurane 8% in N2O 50% and O2 50 % (flow rate –8lit/min) for 30 seconds connected to the face mask. After Loss of eyelash reflex, SGA insertion was attempted. The time taken from induction of anaesthesia to loss of eyelash reflex, time taken from loss of eyelash reflex to successful SGA insertion and hemodynamic parameters at baseline, at induction and every min for 5 minutes after induction were recorded in both the groups. Data was analysed using student’s t-pair test and statistical significance set at P<0.05. Results Successful LMA insertion in first attempt was 100% in group P with excellent conditions while in group S it was 89.067% (57 patients) with excellent to satisfactory conditions. Mean arterial pressure was observed statistically significant between the groups (p=0.03) Conclusion: - Sevoflurane requires greater time for LMA insertion but with better haemodynamic stability. So, it can be used as an alternative.