“EVALUATION OF CORD BLOOD TO SCREEN FOR NEONATAL ANEMIA AND ITS CORRELATION WITH MATERNAL ANEMIA IN A TERTIARY MEDICAL COLLEGE IN EASTERN INDIA”
Author:
Biswas Soumika1, Biswas Lekha2
Affiliation:
1. MBBS,MD (Biochemistry), Assistant Professor, Dept. of Biochemistry, Medical College & Hospital, Kolkata,west Bengal, India. 2. MBBS, MD (Biochemistry), Associate Professor, Dept. of Biochemistry, Rampurhat Govt. Medical College.
Abstract
An estimated 87% of pregnant women in India suffers from iron deciency anemia in some point in their
pregnancy. Maternal anemia has been found to be associated with low birth weight babies, asphyxia,
preterm delivery and neurological decits & the neonatal iron stores are solely dependent on the transplacental iron transport,
about 1gm in term newborns. The transfer of iron from the mother to the foetus is tightly regulated by factors such as transferrin,
coelomic uid and hepcidin. This study aims to nd whether maternal anemia has a correlation with neonatal anemia. Also, it
aims to screen for neonatal anemia based on cord blood evaluation.The parameters used for comparison from cord blood are
serum iron, ferritin and total iron binding capacity (TIBC) and blood hemoglobin concentration. This study was conducted over
a period of two months, from July 22 nd 2021 to September 21 , 2021, in Medical College & Hospital , Kolkata and a total of 124
mother-infant pairs were taken out of which 62 were anemic mothers (Hb<11g/dl) and 62 non anemic. The cord Hb, iron and
ferritin levels were signicantly (p<0.05) lower in the anemic mothers than in the non anemic ones. The cord TIBC in the anemic
group was higher but it was not signicant (p=0.083). There was a moderate positive correlation between mother's Hb and cord
iron levels, r= 0.46, p< 0.00001, a slight negative correlation between mother's Hb and cord TIBC was observed but the values
were not signicant, r= -0.13, p=0.31, serum ferritin in cord blood was found to have moderate positive correlation with
maternal Hb, r= 0.40, p < 0.00001. This study was able to establish a correlation between maternal Hb and cord Hb, iron and
ferritin thus showing that maternal iron status affects the iron prole of the neonate. This emphasises the need for proper iron
and folic acid supplementation during the course of the pregnancy.
Publisher
World Wide Journals
Subject
Paleontology,Stratigraphy,Geology,Building and Construction,Architecture,Human Factors and Ergonomics,Orthopedics and Sports Medicine,Industrial and Manufacturing Engineering,Polymers and Plastics,Mechanical Engineering,Mechanics of Materials,Civil and Structural Engineering,General Physics and Astronomy,Literature and Literary Theory,Linguistics and Language,Language and Linguistics,Psychiatry and Mental health,Clinical Psychology,Development,Geography, Planning and Development,Health Policy,Economics, Econometrics and Finance (miscellaneous),Literature and Literary Theory,Linguistics and Language
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