DIAGNOSIS AND MANAGEMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS IN PREGNANCY: A CASE REPORT
Author:
S. Tankhiwale Mrunmayee1, Waikar Manjushri2, Parpillewar Moushmi3
Affiliation:
1. Senior Resident, Department of Obstetrics and Gynaecology, Government Medical College and Hospital, Nagpur, Maharashtra, India 2. Professor, Department of Obstetrics and Gynaecology, Government Medical College and Hospital, Nagpur, Maharashtra, India 3. Associate Professor, Department of Obstetrics and Gynaecology, Government Medical College and Hospital, Nagpur, Maharashtra, India
Abstract
Systemic lupus erythematosus (SLE) is a heterogenous autoimmune disorder with a complex
pathogenesis that results in interactions between susceptibility genes and environmental factors.
Almost 90 percent of SLE cases are in women; especially in child bearing age. It is a chronic inammatory disease with
multisystemic involvement in which immune complex deposition causes damage to the tissues involved. Maternal and fetal
mortality and morbidity are still signicantly high despite improvements in outcomes. Maternal morbidity includes higher risk of
disease ares, preeclampsia and other pregnancy-related complications. Fetal issues include higher rates of preterm birth,
fetal growth restriction, and neonatal lupus syndromes. Management option is limited to few safer drugs. A multidisciplinary
approach, with close medical, obstetric and neonatal monitoring, is essential for optimal outcomes. This case report describes a
27 years old primigravida diagnosed with SLE for the rst time in pregnancy, evaluated and managed with a good fetomaternal outcome.
Publisher
World Wide Journals
Subject
Microbiology (medical),Histology,Pathology and Forensic Medicine,Infectious Diseases,Microbiology (medical),General Medicine,Infectious Diseases,Microbiology (medical),Infectious Diseases,Microbiology (medical),Public Health, Environmental and Occupational Health,General Immunology and Microbiology,Epidemiology,Nephrology,General Medicine,Nephrology,Psychiatry and Mental health,Arts and Humanities (miscellaneous),Clinical Psychology,Developmental and Educational Psychology,Neuropsychology and Physiological Psychology,General Medicine,General Nursing,Critical Care and Intensive Care Medicine,Nutrition and Dietetics
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