HOLT-ORAM SYNDROME: RARE CASE SERIES

Author:

Reddy Muskula Mahendar1,P Roshin1,J Ajay2,Chetty Sanjeev3

Affiliation:

1. P.G. M.D. Paediatrics, Department of Paediatrics, Navodaya Medical college Hospital and Research Centre, Raichur 584101.

2. Associate professor, Department of Paediatrics, Navodaya Medical college Hospital and Research Centre, Raichur 584101.

3. Professor, Department of Paediatrics, Navodaya Medical college Hospital and Research Centre, Raichur 584101.

Abstract

The upper limb malformations in association with congenital heart defects occurring as autosomal dominant disorder are seen in Holt-Oram syndrome. It is a very rare disorder which can be detected with early prenatal ultrasound checkups. Here we are reporting two cases of holt-oram syndrome

Publisher

World Wide Journals

Reference7 articles.

1. McDermott DA, Fong JC, Basson CT. Holt-Oram Syndrome. 2004 Jul 20 [updated 2019 May 23]. In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2020.

2. Krauser AF, Ponnarasu S, Schury MP. Holt Oram Syndrome. 2020 Aug 30. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2020 Jan–

3. Bossert T, Walther T, Gummert J, Hubald R, Kostelka M, Mohr FW. Cardiac malformations associated with the Holt-Oram syndrome--report on a family and review of the literature. ThoracCardiovasc Surg. 2002 Oct;50(5):312-4.

4. Virdis G, Dessole M, Dessole S, Ambrosini G, Cosmi E, Cherchil PL, Capobianco G. Holt Oram syndrome: a case report and review of the literature. ClinExpObstet Gynecol. 2016;43(1):137-9.

5. Tidake A, Gangurde P, Shaikh Z, Mahajan A. Tetralogy of Fallot with Holt-Oram syndrome: case report and review. Clin Res Cardiol. 2015 Sep;104(9):790-3.

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