Affiliation:
1. PG Resident 3 year.
2. Head of department, Saraswathi institute of medical sciences, hapur, Uttar Pradesh
3. Assistant Professor, SIMS, Hapur
Abstract
troduction: Anal ssure is a non-healing linear tear in the distal anal mucosa below the dentate line and is a painful entity.Fissure in ano is a
common proctologic disease affecting both men and womenparticularly young.They require surgery like manual anal dilation or lateral internal
sphincterotomy which heal the ssure in more than 90% cases but with a signicant risk of impaired anal continence. Newer non surgical therapies
such as topical 2% diltiazem gel, have shown good efcacy without impairing anal continence. The aim of the study is to compare the AIMefcacy of outcome of Lateral Sphincterotomy Versus 2% Diltiazem gel in the treatment of chronic ssure in ano. 70 Material and Methods:
patients diagnosed with ssure in ano were randomly divided into 2 %Diltiazem and lateral sphincterotomy groups. Patient were followed up at
regular interval for symptomatic relief and healing of ssure. Less 89.4% patients Result: in diltiazem group and 100% of patients in lateral
internal sphicterotomy group ssure healed completely between 4-8 weeks. In the diltiazem group pain relief was fairly good. 42 patients (89.4%)
had pain relief at the end of 14 weeks. But the pain relief in lateral internal sphincterotomy group was excellent with 100% patients having complete
pain relief by 8 weeks. Mild headache was experienced with diltiazem patients.1 patient complained of atus incontinence with lateral internal
sphincterotomy. We conclude that lateral sphincterotomy is the gold standard t Conclusion: reatment for the ssure in ano but chemical
sphincterotomy using 2% topical diltiazem gel can be considered a good second line treatment option in those unt for surgery or for those not
willing for surgery
Subject
General Agricultural and Biological Sciences,Philosophy,Classics,Physical and Theoretical Chemistry,Mechanical Engineering,General Chemical Engineering,Infectious Diseases,Cell Biology,Cellular and Molecular Neuroscience,Biochemistry,Law,Social Sciences (miscellaneous),History,General Economics, Econometrics and Finance,Business and International Management,Mechanical Engineering,Ocean Engineering,Aerospace Engineering,Condensed Matter Physics,Nuclear Energy and Engineering,Civil and Structural Engineering,Statistical and Nonlinear Physics,Statistics and Probability,Industrial and Manufacturing Engineering,Management Science and Operations Research,Statistics, Probability and Uncertainty,Statistics and Probability
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