MANAGEMENT OF POST-SURGICAL INFLAMMATION WITH PROTEOLYTIC ENZYME-BIOFLAVONOID COMBINATION

Author:

Dhadiwal Rajesh1,Tiwari Shashank2,Kumar Jauhari Ramendra3

Affiliation:

1. MBBS, DNB, D Ortho, Director, Dhadiwal Hospital, Nashik, Maharashtra, India.

2. BDS, Consultant Dentist, M V Hospital and Research Centre, Lucknow, Uttar Pradesh, India.

3. MS Surgery, Associate Professor, Department of Surgery, Ganesh Shankar Vidyarthi Memorial Medical College, Kanpur, Uttar Pradesh, India.

Abstract

Surgical care is an integral component of health systems, and so is the appropriate management of the surgical wound. Excessive inammation and edema, in the post-surgical period, can result in delayed wound healing, infective complications and increased length of hospital stay, among other complications. Systemic enzyme therapy (SET) with trypsin and bromelain, in combination with the bioavonoid rutoside, has been extensively investigated as alternatives to conventional therapies for pain and swelling associated with many inammatory conditions. The multi-pronged pharmacodynamic action of these ingredients on different inammatory processes has been highlighted in this review. Additionally, clinical studies demonstrating the benecial effects of SET in multiple surgical settings, including general surgical, dental, orthopaedic, cosmetic surgeries, are also discussed

Publisher

World Wide Journals

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