SECRETORY CARCINOMA OF ENDOMETRIUM: A MORPHOLOGICAL MIMICKER POSING DIAGNOSTIC DILEMMA

SECRETORY CARCINOMA OF ENDOMETRIUM: A MORPHOLOGICAL MIMICKER POSING DIAGNOSTIC DILEMMA - A RARE CASE

Published:2021-07-01 Issue: Volume: Page:32-33
ISSN:
Container-title:INDIAN JOURNAL OF APPLIED RESEARCH
language:en
Short-container-title:IJAR

Author:

V C Dharani¹,H K Manjunath²,Mohan Bhargavi³,B M Varaprasad⁴,M J Thej³

Affiliation:

1. (Associate Professor)Dept. of Pathology, BGS Global Institute of Medical Sciences, Bengaluru-560060.

2. (Professor & Head)Dept. of Pathology, BGS Global Institute of Medical Sciences, Bengaluru-560060.

3. (Associate Professor)Dept. of Pathology, BGS Global Institute of Medical Sciences, Bengaluru-560060

4. (Assistant Professor)Dept. of Pathology, BGS Global Institute of Medical Sciences, Bengaluru-560060

Abstract

BACKGROUND: Secretory carcinoma of the endometrium, a rare subtype of endometrioid carcinoma morphologically resembles the early secretory phase of endometrium and is almost always well differentiated and carries excellent prognosis. Very few cases of secretory carcinoma have been reported in the literature till date. Case presentation:A 58 yr old obese female presented with post-menopausal bleeding. Ultrasound revealed increased endometrial thickness and endometrial biopsy showed hyperplasia without atypia in secretory transformation. Pathological examination of the hysterectomy specimen revealed features of secretory carcinoma of the endometrium as an incidental nding. CONCLUSION: Secretory carcinoma, a rare subtype of well differentiated endometrial carcinoma carries very good prognosis and morphologically mimics various pathological conditions of endometrium. Hence, this needs to be carefully evaluated morphologically in addition with immunohistochemical markers to arrive at an accurate diagnosis.

Publisher

World Wide Journals

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