CAN THYROID PROFILE PREDICT THE IMPENDING DANGER OF DECOMPENSATION IN LIVER CIRRHOSIS?
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Published:2023-01-01
Issue:
Volume:
Page:73-75
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ISSN:
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Container-title:INDIAN JOURNAL OF APPLIED RESEARCH
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language:en
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Short-container-title:IJAR
Author:
Priyanka Injeti Keerthi1, Mounika Atchala2, Chytanya Paka Atchuta3, Parise Gandhi4
Affiliation:
1. M.D. Gen Med, Assistant Professor, Department of General Medicine, Government General hospital, Guntur, India 2. M.D. Gen Med Junior Resident, Department of General Medicine, Government General hospital, Guntur, India 3. M.D. Gen Med Associate Professor, Department of General Medicine, Nimra Institute of medical sciences, Vijayawada, India 4. Parise
Abstract
Background: Chronic liver disease is one of the world's leading causes of mortality and morbidity. Thyroid and liver are
interdependent in their functioning, Thyroid gland regulates basic metabolic rate in hepatocytes and liver being the site of
thyroid hormone metabolism, modulates hormone levels. Assessment of thyroid levels in cirrhosis may prove useful to identify severity of
disease and probability of complication rates. In this context we conducted a study to signify the association between thyroid hormones and
severity of hepatic disorder in cirrhosis through usage of Child Pugh score. 100 patients a Method: ged 18 years and above, with liver cirrhosis
were evaluated in our institute. Thyroid prole and other relevant investigations were carried out to assess severity of liver cirrhosis, correlated
with Child Pugh scoring. Results: 74% of the patients in the study were in euthyroid state. Total and free T3, T4 levels were signicantly low and
inversely correlated with severity of liver cirrhosis. Most of the patients had normal T4 and TSH levels. Among all, free T3 was found to be the
most sensitive marker to assess severity of cirrhosis. Thyroid dysfunction is oft Conclusion: en observed in liver cirrhosis which calls for thyroid
prole tests to be conducted with a potential role as prognostic marker.
Publisher
World Wide Journals
Subject
Cellular and Molecular Neuroscience,Developmental Neuroscience,Neurology,Toxicology,General Neuroscience,Toxicology,General Neuroscience,Cellular and Molecular Neuroscience,Developmental Neuroscience,Toxicology,Nuclear and High Energy Physics,Atomic and Molecular Physics, and Optics,Anthropology,Visual Arts and Performing Arts,Speech and Hearing,Public Health, Environmental and Occupational Health,Otorhinolaryngology,Mechanical Engineering,Acoustics and Ultrasonics,Mechanics of Materials,Condensed Matter Physics,General Materials Science,General Engineering,Industrial and Manufacturing Engineering,Public Health, Environmental and Occupational Health,Mechanical Engineering,Acoustics and Ultrasonics,Aerospace Engineering,Automotive Engineering,Building and Construction
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