A COMPARATIVE STUDY OF INTRATHECAL DEXMEDETOMIDINE WITH 0.5% HYPERBARIC BUPIVACAINE AND INTRATHECAL FENTANYL WITH 0.5% HYPERBARIC BUPIVACAINE IN INFRA UMBILICAL SURGERIES

Abstract

INTRODUCTION: Regional anaesthesia is the preferred technique for most infra-umbilical surgeries. It allows the patient to remain awake, minimizes or completely avoids the problem associated with airway management. With spinal anaesthesia, the onset of anaesthesia is more rapid allowing the surgical incision to be made sooner and also provides post operative analgesia. AIM: To determine the duration of analgesia determined by the rst demand for rescue analgesia in two groups of a dened study population. To compare intraoperative hemodynamics between two groups of population. To note the incidence of any complications in either group, specically sedation and pruritus. MATERIALS AND METHODS: This study was undertaken in Command Hospital (EC), Kolkata (West Bengal, India) during the period Mar 2017 to Feb 2018. One hundred twenty patients, scheduled for infra-umbilical surgeries belonging to ASAI and II were included in the study. The study population was randomly divided into two groups with 60 patients in each group. RESULT: Association of ASA vs. group was not statistically signicant (p=0.6985). Association of Comorbidity vs. group was not statistically signicant (p=0.9833). Association of diagnosis/surgery vs. group was statistically signicant (p=0.0301). We found that in group-I, the mean duration of motor block (mean ± s.d.) of patients was 359.3333 ± 34.3431 min. In group-II, the mean duration of motor block (mean ± s.d.) of patients was 265.7167 ± 28.4737 min. Difference of mean duration of motor block vs. group was statistically signicant (p<0.0001). CONCLUSION:Intrathecal dexmedetomidine with 0.5% hyperbaric bupivacaine produces excellent surgical analgesia and an extended analgesia in postoperative period. Intrathecal dexmedetomidine with 0.5% hyperbaric bupivacaine increases the duration of sensory and motor blockade.