UNRAVELLING THE GENETIC ETIOLOGY OF NON-SYNDROMIC HEREDITARY GINGIVAL FIBROMATOSIS: A LITERATURE REVIEW AND CASE REPORT

Author:

Ansari Nasreen1,Kaur Lamba Arundeep2,Faraz Farrukh3,Tandon Shruti4,Dhingra Sachin5

Affiliation:

1. Junior Resident, Department of Periodontics, Maulana Azad Institute of Dental Sciences, Delhi

2. Professor and Head of Department, Department of Periodontics, Maulana Azad Institute of Dental Sciences, Delhi

3. Professor, Department of Periodontics, Maulana Azad Institute of Dental Sciences, Delhi.

4. Professor, Department of Periodontics, Maulana Azad Institute of Dental Sciences, Delhi

5. Senior Resident, Department of Periodontics, Maulana Azad Institute of Dental Sciences, Delhi

Abstract

Hereditary gingival bromatosis is a rare condition that affects the gingiva and is characterized by a benign, brous overgrowth that can occur alone or as part of a syndrome. Clinically, it is associated with a pink gingiva with distinct stippling that covers nearly the entire tooth surface, frequently preventing their eruption. It is frequently reported during the transition from primary to permanent dentition, which left untreated may have a negative psychological impact at that age. The aim of this review is to provide a clinical insight, as well as a summary and discussion of the role of potential genes, chromosomal regions, and genetic variations in the pathogenesis of this rare disease. In addition, this paper describes a family with a non-syndromic form of hereditary gingival bromatosis exhibiting signicant clinical variability, ranging from severe generalized gingival overgrowth in a 19-year-old boy, to minimal manifestations in his maternal grandmother. The treatment modality used to treat this patient and measures taken to prevent the recurrence of this condition have also been discussed in detail.

Publisher

World Wide Journals

Subject

Paleontology,Aquatic Science,Oceanography,Linguistics and Language,Language and Linguistics,Industrial and Manufacturing Engineering,Polymers and Plastics,Materials Science (miscellaneous),Communication,Cultural Studies,Electrical and Electronic Engineering,Signal Processing,Electronic, Optical and Magnetic Materials,Biotechnology,Electrical and Electronic Engineering,Instrumentation,Industrial and Manufacturing Engineering,Safety, Risk, Reliability and Quality,General Chemical Engineering,Electrical and Electronic Engineering,Atomic and Molecular Physics, and Optics,Electrical and Electronic Engineering,Industrial and Manufacturing Engineering

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