A PROSPECTIVE STUDY TO COMPARE LOCAL CONTROL OF DISEASE BY DEFINITIVE CHEMORADIOTHERAPY ALONE AND WITH INTRALUMINAL BOOST IN PATIENTS OF CARCINOMA ESOPHAGUS

Author:

Meena Ramraj,Sharma Rameshwaram,Agrawal Shivani,Sharma Vishakha,Kakka Abhinav

Abstract

As per Globocan 2020 , estimated no. of cases of carcinoma esophagus among men worldwide are 4,18,350 accounting 4.2 % of total cancer th [1] cases and in India , it ranks 5 with an incidence of 63,180 cases . Because esophagus has no serosal covering with extensive, longitudinal connecting system of lymphatic plexus, direct invasion to [2] contiguous structures and lymph node metastasis occurs early. That is why, unresectable or metastatic disease at the time of diagnosis is seen in approximately 80% of patients, with cure rate <15% and thus making esophageal cancer one of the most dreaded malignancies with [1,3] a death rate of 5.5% worldwide

Publisher

World Wide Journals

Reference18 articles.

1. WHO; IARC; Latest global cancer data: Cancer burden rises to 18.1 million new cases and 9.6 million cancer deaths in 2020 Press Release Geneva,Switzerland: 12 September 2020

2. Perez CA, Brady LW, Halperin EC. Principles and Practice of Radiation Oncology. 7th ed. Philadelphia, PA: Lippincott Williams and Wilkins; 2018. p. 3789-91

3. Pearson JG. The present status and future potential of radiotherapy in the management of esophageal cancer. Cancer 1977;39:882-90.

4. Khan NA, Lone MM, Fir A, Kharadi MY, et.al. Clinicopathological Profile of Carcinoma esophagus and esophagogastric Junction in Kashmir. JK-Practioner 2004; 11:182-185.

5. Esophageal cancer: epidemiology, pathogenesis and prevention. Nat ClinPractGastroenterolHepatol 2008; 5: 517-526 [PMID: 18679388 DOI: 10.1038/ncpgasthep1223])

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