Abstract
Autoimmune encephalitis is one of the main causes of
noninfectious encephalitis. Can be broadly classied into
non-paraneoplastic, paraneoplastic and vasculitis
associated encephalopathy. It can be triggered by tumors and
infections. Autoimmune encephalitis presents with variety of
clinical features such as acute onset behavioral changes,
psychiatric symptoms, memory loss, movement disorders,
dystonia, mutism and seizures. Neuronal antibodies are
directed against cell surface Ag(CSAab) ,synaptic antigen
(SyAab), intraneuronal Ag(INAab). Anti LG1 and CASPR2
encephalitis are usually non-neoplastic autoimmune
encephalopathy where antibodies are directed against
proteins associated with Voltage gated k channel. About 50%
patients with anti-VGKC encephalitis do not present
antibodies against LGI1 or CASPR-2. Anually 1 case is
detected amongst 100000 patients. This is a case report of a
patient presented to Geriatrics OPD and the series of
evaluation which led to diagnosis and treatment outcome.
Subject
Organizational Behavior and Human Resource Management,Applied Psychology,Ecology, Evolution, Behavior and Systematics,Sociology and Political Science,Philosophy,Religious studies,Education,Library and Information Sciences,Museology,Information Systems,History,Visual Arts and Performing Arts,History and Philosophy of Science,Health Policy,General Medicine,Issues, ethics and legal aspects,General Medicine,Organic Chemistry,Drug Discovery,Pharmacology,Management, Monitoring, Policy and Law,Nature and Landscape Conservation,Ecology,Pharmacology (medical),Drug Discovery,Pharmaceutical Science,Pharmacology