Affiliation:
1. Senior Resident Dept. Of Radio Diagnosis, PGIMS, Rohtak.
2. Junior Resident, Dept. Of Obstetrics And Gynaecology, PGIMS, Rohtak
Abstract
Neonatal cholestasis is a diagnostic dilemma in clinical practice. It is a serious condition with varied etiological factors. Biliary atresia, hepatitis, and choledochal cyst are common causes in a neonate. (2) Intrahepatic and extrahepatic causes can be easily differentiated by radiological investigations. Inspissated bile syndrome (3),(4) is a rare cause of neonatal jaundice. Predisposing factors for the development of inspissated bile in neonates include (5) hemolysis, prematurity, parenteral nutrition, sepsis, and diuretic therapy . Ultrasonography is valuable in diagnosing the causes of obstructive jaundice, especially in neonates where computed tomography scans cannot be done due to radiation exposure and MRI cannot be done due to the motion artifacts. Hepatobiliary scintigraphy single-photon emission computer tomography (HBS SPECT) is the most reliable diagnostic method. Generally, inspissated bile resolves spontaneously, but sometimes patients need ursodeoxycholic acid. Rarely surgical drainage is also needed.
Subject
Law,Cultural Studies,Demography,General Economics, Econometrics and Finance,Political Science and International Relations,Sociology and Political Science,Statistics, Probability and Uncertainty,Economics and Econometrics,Statistics and Probability,Plant Science,Aquatic Science,Economics and Econometrics,Finance,Management, Monitoring, Policy and Law,Ecology,Aquatic Science,Ecology, Evolution, Behavior and Systematics,General Medicine,Economics, Econometrics and Finance (miscellaneous),General Earth and Planetary Sciences,General Environmental Science,General Economics, Econometrics and Finance,Political Science and International Relations,Sociology and Political Science,History,Cultural Studies
Reference10 articles.
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