COMPARATIVE STUDY OF CLINICO-RADIOLOGICAL AND MYCOBACTERIAL PROFILE OF PULMONARY TB IN DIABETIC VS. NON DIABETIC PATIENTS AT TERTIARY CARE HOSPITAL

Abstract

Background: Tuberculosis (TB) is a disease most commonly affecting the lungs caused by mycobacterium tuberculosis, may also affect any parts of the body. Diabetes mellitus (DM) is recognized as a major risk factor for the progression of active pulmonary tuberculosis (PTB). The prole of pulmonary tuberculosis is variable in diabetic vs non diabetic patients .There is scarcity of published comparative literature, therefore this study carried out. This is hospital based prospective observational and comparative study was conducted in admitted patients of MahatmaMethod: Gandhi Medical College & Hospital, Jaipur. All the new cases of pulmonary tuberculosis diagnosed on the basis of clinic-radiological and mycobacterial. All the tuberculosis patients were also screened for diabetes as per criteria and divided in 2 groups PTB-DM & PTB-NDM respectively. Total number of cases of pulmonary tuberculosis in the study was 150, out of which 50 cases with diabetic and 100 casesResults: without diabetic. Male's predominance was in both the groups (70%vs78%). Maximum cases of PTB were in middle age (41-60 years) in both the groups (54% vs51%). There was no signicant difference in respiratory symptoms, mycobacterial positivity and various type parenchymal lesions. However there was signicantly more grade 3 positivity on Z.N staining, lower zone predominance, multiple cavitations and far advance disease in diabetic PTB patients Diabetes is a risk factor & potentially may affect serious implications in management of tuberculosis and TB. Conclusion: control program. Therefore, early detection of diabetes in suspect cases of pulmonary tuberculosis &vice-versa is important in clinical practice & TB control program.