A STUDY OF SERUM LEVELS OF 25 (OH)VITAMIN D AND CALCIUM IN PRE-ECLAMPSIA, ECLAMPSIA AND NORMAL HEALTHY PREGNANT WOMEN-Reference-Cited by-同舟云学术

A STUDY OF SERUM LEVELS OF 25 (OH)VITAMIN D AND CALCIUM IN PRE-ECLAMPSIA, ECLAMPSIA AND NORMAL HEALTHY PREGNANT WOMEN

Published:2021-11-01 Issue: Volume: Page:1-5
ISSN:
Container-title:INDIAN JOURNAL OF APPLIED RESEARCH
language:en
Short-container-title:IJAR

Author:

Garg Rama¹,Monika Monika²,Kaur Parneet³,Singh Jasvir⁴

Affiliation:

1. Retired Associate Professor Department of Obstetrics & Gynaecology Government Medical College Patiala 147001, Punjab, India.

2. Senior Resident Department of Obstetrics & Gynaecology Government Medical College Patiala 147001, Punjab, India

3. Professor & Head Department of Obstetrics & Gynaecology Government Medical College Patiala 147001, Punjab, India

4. Associate Professor Department of Biochemistry Government Medical College Patiala 147001, Punjab, India

Abstract

BACKGROUND- It is important to know the modiable risk factors related to the occurrence of preeclampsia and eclampsia, which can help in its primary prevention. To study the serum levels of 25(OH)Vitamin-D and OBJECTIVESCalcium in pre-eclampsia, eclampsia, and normal healthy pregnant women. The prospective observational MATERIAL AND METHODS- study was conducted from 2018-2021 in the Department of Obstetrics and Gynecology, Government Medical College, Northern India. Eighty women were divided into 3 groups: Group A- women with preeclamp sia (30); Group B -women with eclampsia (30); Group C– normal healthy pregnant women (20). Investigations: 1. S.25(OH) VIT D level; 2. S. Calcium level. Results- The mean ± SD levels of vitamin D in women of Group A (preeclampsia) was 21.40 ± 7.11, in Group B (eclampsia) was 16.98 ± 6.62 and in Group C (normal healthy pregnant women) was 37.86 ± 11.34. This data is statistically signicant (P=0.016). The mean ± SD of levels of serum calcium in women of Group A (preeclampsia) was 8.68 ± 0.63, in Group B (eclampsia) was 7.86 ± 0.90 and in Group C (normal healthy pregnant women) was 9.07 ± 0.50. The difference between groups was statistically signicant (P=0.018). Both S. Vitamin D and S. Calc CONCLUSION- ium levels have a negative correlation with systolic and diastolic blood pressure. Women having decreased levels of S. Vitamin D and S. Calcium are more prone to develop hypertensive disorders of pregnancy

Publisher

World Wide Journals

Reference28 articles.

1. Cunningham FG, Leveno KJ, Bloom SL, Dashe JS, Hoffman BL, Casey BM et al. (2018), “Hypertensive Disorders.” Williams OBSTETRICS 25th EDITION. McGraw-Hill Education. 40:710-16.

2. Priyanka S, Rajini B. (2017), “The study of serum calcium in pregnancy induced hypertension and normal pregnancy and its correlation with pregnancy induced hypertension.” MedPulse International Journal of Physiology. 3(3):37-41.

3. Hyppönen E, Power C. (2007), “Hypovitaminosis D in British adults at age 45 y: nationwide cohort study of dietary and lifestyle predictors.” Am J ClinNutr, 85:860–8.

4. Bodnar LM, Catov JM, Roberts JM, Simhan HN. (2007), “Prepregnancy obesity predicts poor vitamin D status in mothers and their neonates.” J Nutr, 137:2437–4

5. Satyanarayan U., Chakrapani U. Biochemistry. (2006) “Vitamins.” Books and Allied (P) Ltd. 4th edition, Pg. 124-127.