ROLE OF DIFFUSION WEIGHTED IMAGING AND ADC VALUES IN CHARACTERISING BREAST LESIONS ON MR MAMMOGRAPHY

Abstract

Background- Dynamic contrast enhanced MRI (DCE MR) is an important imaging modality to detect and evaluate the breast lesions with high sensitivity. Aim of study was to characterize breast lesions detect Objective- ed on MR mammography by diffusion weighted imaging and quantify ADC values to differentiate benign and malignant mass and non mass lesions. Methods- This prospective study was performed in thirty female patients on 1.5T GE Healthcare HDXT MRI machine. Thirty three breast lesions were included in this study. Final diagnosis was correlated with histopathological diagnosis. Out of total thirty three lesions, mean ADC value Results- of malignant lesions was 1.01 ± 0.24 x 10-3mm2/sec and for benign lesions was 1.48 ± 0.29 x 10-3 mm2/sec. The calculated ADC cut off value of 1.22x 10-3 mm2/sec gave a sensitivity of 86.96% and specicity of 90% to differentiate malignant and benign breast lesions. As a Conclusion- conclusion Diffusion weighted imaging and quantitative analysis with ADC values can be used with conventional DCE MR to differentiate benign and malignant breast lesions with high sensitivity and specicity