ACUTE CORONARY SYNDROME FOLLOWING INTRAVENOUS IMMUNOGLOBULIN THERAPY : A HIDDEN RISK-Reference-Cited by-同舟云学术

ACUTE CORONARY SYNDROME FOLLOWING INTRAVENOUS IMMUNOGLOBULIN THERAPY : A HIDDEN RISK

Published:2021-06-01 Issue: Volume: Page:78-79
ISSN:
Container-title:INDIAN JOURNAL OF APPLIED RESEARCH
language:en
Short-container-title:IJAR

Author:

Rajachandran Karthikkeyan¹,Varghese Giphy Susan²

Affiliation:

1. MD(Anesthesia), IDCCM, FNB(Critical Care Medicine), Consultant and Chief, Medical Intensive Care Unit, PSG SSH, Coimbatore, Tamil Nadu- 641004.

2. Pharm D, Clinical Pharmacist, Medical Intensive Care Unit, PSG SSH, Coimbatore, Tamil Nadu- 641004.

Abstract

Intravenous immunoglobulin (IVIG) is one of the main line modalities of therapy for chronic inammatory demyelinating polyneuropathy (CIDP). We hereby, report an incidence of acute myocardial infarction probably induced by IVIG during the treatment of CIDP. A 76 year old female with no history suggestive of cardiovascular disease, developed an acute Non ST Segment Elevation Myocardial Infarction (NSTEMI) and severe left ventricular dysfunction after receiving three doses of IVIG. Since hypercoagulability is a concern with IVIG therapy, it was discontinued. Hence, we highlight the importance of cardiac evaluation before initiation and during the course of IVIG therapy in elderly patients as well as in patients with known risk factors for cardiovascular disease and thrombotic events.

Publisher

World Wide Journals

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