A COMPARATIVE STUDY OF THE EFFICACY OF INTRAVENOUS PARACETAMOL AND DEXMEDETOMIDINE ON PERI OPERATIVE HEMODYNAMICS AND POST OPERATIVE ANALGESIA FOR PATIENTS UNDERGOING LAPAROSCOPIC SURGERY

Abstract

Perioperative hemodynamic instability is one of the known complication ofLaproscopic surgeries. CO2 insufation causes increased abdominal pressure and hypercapnia which will contribute to undesirable hemodynamic changes. Dexmedetomidine when administered as a loading dose causes sedative , hypnotic, anxiolytic, analgesic and sympatholytic effect. In ths study 60 Patients were randomised in two groups 30 each . Group 1/ Group P recieved 1gm paracetamol diluted in 100 ml 0.9% Normal saline IV over 10 minutes before induction. Group 2/Group D Bolus -1mcg/ kg diluted in 100 ml 0.9% Normal saline IV over 10 minutes before induction. Perioperative Hemodynamic parameters , post operative analgesia were compared. Increase in heart rate , blood pressure were found to be more in Group 1/Group P compared to Group 2/ Group 2/ Group D. Patients in both groups had moderated pain postoperatively and requires rescue analagesia after extubation. We observed the use of Dexmedetomidine is very effective in managing Perioperative Hemodynamic instability when compared to paracetamol