EVALUATION OF THE OUTCOME OF ORAL VERSUS VAGINAL MISOPROSTOL IN TERMINATION OF ALL CASES OF INTRAUTERINE FETAL DEATH-Reference-Cited by-同舟云学术

EVALUATION OF THE OUTCOME OF ORAL VERSUS VAGINAL MISOPROSTOL IN TERMINATION OF ALL CASES OF INTRAUTERINE FETAL DEATH

Published:2022-05-01 Issue: Volume: Page:5-8
ISSN:
Container-title:INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH
language:en
Short-container-title:ijsr

Author:

P Sasikumar Sarannya¹,Kuriyan Annie²,Daniel Saley³,S Panicker Brij⁴

Affiliation:

1. Postgraduate Student, Dept. Of Obstetrics And Gynaecology, Jubilee Mission Medical College & Research Institute, Thrissur.

2. Professor, Dept. of Obstetrics and Gynaecology, Jubilee Mission Medical College & Research Institute, Thrissur

3. Associate Professor, Dept. of Obstetrics and Gynaecology, Jubilee Mission Medical College & Research Institute, Thrissur.

4. Assistant Professor, Dept. of Obstetrics and Gynaecology, Jubilee Mission Medical College and Research Institute, Thrissur.

Abstract

Introduction: Misoprostol a potent uterotropic and uterotonic agent which causes cervical effacement &dilatation and stimulates myometrial contractions, is effective in terminating intrauterine foetal death. The Objective of the study was to compare the effectiveness of oral misoprostol versus vaginal misoprostol in termination of all cases of intrauterine foetal death and its outcome. Details of induction –delivery interval and maternal morbidities were also analysed. A prospective comparative study.Al Methodology: l pregnant women indicated for termination of intrauterine foetal death satisfying both inclusion and exclusion criteria being admitted in our Labour Room during the period of this study were included.Total 60 patients were included out of which 30 receiving oral misoprostol forms the rst group and the other 30 receiving vaginal misoprostol forms the second group. For the rst group, 200 mcg of oral misoprostol tablet was dissolved in 200ml water and 25 mcg, ie. 25ml of the solution was given rst and then every two hours till pain occurs. Second group was given 25 mcg of vaginal misoprostol every 4 hourly. Induction-delivery interval and maternal morbidities were compared in both groups. The me Results: an induction-delivery interval was higher in Oral misoprostol when compared to vaginal route and this difference was found to be statistically signicant (p <0.001). However, the oral route was much easier when compared to vaginal route.The maternal morbidities like diarrhoea, fever, PPH, shivering, vomiting and tachysystole were similar in both groups.There were no cases of uterine rupture in the study. The effe Conclusion: ctiveness of different routes of administration was signicant in our study with signicantly shorter mean induction-delivery interval in vaginal route compared to oral route.Although there were few maternal morbidities seen in both groups, there were no statistically signicant differences between two groups

Publisher

World Wide Journals

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