HISTOPATHOLOGICAL STUDY OF TUMOURS AND TUMOUR LIKE LESIONS OF KIDNEY AND RENAL PELVIS

Abstract

Background : Tumour and tumour like lesions of kidney and renal pelvis include a wide spectrum of entities. Renal neoplasms occurs both in adults and in children, with few rare tumours and account for 1% to 2% of all body cancers. Majority of which are RCC. Tumour and tumour like lesions of kidney and renal pelvis may present with nonspecic clinical manifestations, incidental ndings on radiology or at autopsy, may present with the classical triad of ank pain, haematuria and abdominal mass or can be asymptomatic. Hence histopathological examination is essential for the diagnosis of renal neoplasms. Material and method : It is retrospective study (July 2003 to June 2013) for a period of 10 years. Histopathological features of 38 tumours and tumour like lesions of the kidney and renal pelvis were analysed.Out of 38 cases, 27 were nephrectomy specimens and 11 were renal biopsies The histopathological reports and clinical details were collected and corresponding slides were reviewed. Tumours are classied according to WHO classication 2016. Results: The present study included 38 cases of tumour and tumour like lesions of kidney and renal pelvis. Histopathological evaluation revealed malignant neoplasms in 27 (71.05%) cases, benign neoplasm in 5 (13.15%) cases and tumour like lesions in 6 (15.79%) cases.Among malignant tumours, clear cell RCC was the most frequent tumour in our study observed in 13 (86.67%) cases. Overall higher numbers of tumours and tumourth th like lesions of kidney and renal pelvis were seen in the rst decade of life followed by 4 to 5 decade of life in our study with a male predominance having M:F ratio of 1.23:1. Conclusion: Malignant tumours outnumbered the benign tumours. Most of the malignant, benign and tumour like lesions present with similar clinical features hence histopathology remains the gold standard method.