HISTOPATHOLOGICAL PROFILE OF PATIENTS OF NEPHROTIC SYNDROME IN A TERTIARY CARE CENTRE OF ROHILKHAND REGION

Abstract

In this retrospective observational study, we intended to assess the histopathological prole of NS in individuals who went through renal biopsy. Individuals were classied into three groups depending on the age at the time of renal biopsy. A total of 100 patients having NS were involved in this study. Symptoms like microhematuria, hypertension, renal failure, oliguria, hypoalbuminemia, anemia and hyperlipidemia were observed. The majority of the individuals included in the study on random basis were males. Minimal change disease comprised 24 percent of the total cases and was majorly seen in the age groups of 0-19 years. Focal segmental glomerulonephritis comprised 26 percent of the total cases and was majorly observed in the 20–60-year age group. The majority of the cases belonged to the membranous glomerulonephritis comprising of 42 percent of the total cases and majorly seen in the 20 – 60-year age group. Membranoproliferative glomerulonephritis and IgA nephropathy comprised of 4 percent of the total cases.