PROTEIN C DEFICIENCY CAUSING RECURRENT DEEP VEIN THROMBOSIS (DVT) IN A YOUNG MALE: CASE REPORT.-Reference-Cited by-同舟云学术

PROTEIN C DEFICIENCY CAUSING RECURRENT DEEP VEIN THROMBOSIS (DVT) IN A YOUNG MALE: CASE REPORT.

Published:2023-01-15 Issue: Volume: Page:75-76
ISSN:
Container-title:GLOBAL JOURNAL FOR RESEARCH ANALYSIS
language:en
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Author:

Sahil Kubal¹,Taori Badal²,Ghanekar Jaishree³

Affiliation:

1. Junior Resident - 3, General Medicine

2. Assistant Professor, General Medicine

3. Professor, General Medicine

Abstract

Protein C deciency (PCD) is a rare genetic disorder that occurs due to mutation in PROC gene and results in increased predisposition to thrombosis, PCD can be 'autosomal dominant 'which is relatively more common occurs in adults and usually presents as recurrent DVT, ischemic colitis or may remain asymptomatic. 'Autosomal recessive PCD' is relatively rare, more severe and presents in neonates as 'neonatal purpura fulminans'. I report a case of 41-yearold male who came with history DVT (recurrent) and diagnosed as 'Protein C deciency: Type 1'

Publisher

World Wide Journals

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Plant Science,Physiology,Biochemistry,Insect Science,Plant Science,Infectious Diseases,Cell Biology,Microbiology (medical),Ecology, Evolution, Behavior and Systematics,Parasitology,Plant Science,Agronomy and Crop Science,Plant Science,Plant Science,Ecology, Evolution, Behavior and Systematics,Complementary and alternative medicine,Pharmacology,Pharmacology,Dermatology

Reference11 articles.

1. Mariam S. Al Harbi , Ayman W . H –Hattab , “ Protein-C Deficiency Caused by a Novel Mutation in the PROC Gene in an Infant with Delayed Onset Purpura Fulminans “, Hindawi , Case Reports in Dermatological Medicine , Volume – 2017.

2. S. Chakravarty , S. Acharyya , M . Mahapatra , “Congenital Protein C deficiency causing major arterial thrombosis in a neonate “, BMJ Case Report – 2019.

3. P.C. Cooper , M. Hill , R.M. Maclean , “The phenotypic and genetic assessment of Protein C deficiency” , International Journal o laboratory Hematology ,Vol-34, no-4, Pg 336-346 , 2012.

4. U. Song , Y. Ryu , K. Hong , Et al , “Severe protein C deficiency in a newborn caused by a homozygous pathogenic variant in the PROC gene : a case report “ , BMC Pediatrics -2021 ; 21 (453).

5. Reza Afghani , Hadi G. , F . Kor , P. Kharazm , “ Protein C Deficiency : Report of a challenging case with recurrent multiorgan thrombosis “ , International Journal of Surgery Case Reports , Sept- 2021.