A CROSS SECTIONAL STUDY OF POLY CYSTIC OVARIAN SYNDROME (PCOS) AMONGST ADOLESCENT GIRLS IN LUCKNOW.

Abstract

Background: Polycystic ovary disease is a common endocrine condition which is rapidly gaining epidemic proportions. Objectives: Current study was undertaken to screen adolescents and young unmarried girls aged 15-24 years for PCOS. Material and Methods: A cross-sectional hospital-based study was undertaken in Lucknow to assess the prevalence of polycystic ovarian syndrome (PCOS) among 389 adolescents and young girls aged 15-24 years. Among them, 300 completed all clinical, ultrasonography (USG), and biochemical investigations. Results: The prevalence of PCOS among them was 22.5% by Rotterdam and 10.7% by Androgen Excess Society criteria. Nonobese comprised 71.8% of PCOS diagnosed by Rotterdam criteria. Mild PCOS (oligomenorrhea and polycystic ovaries on USG) was the most common phenotype (52.6%). History of oligomenorrhea had a positive predictive value of 93.3% and negative predictive value of 86.7% to detect a possible case of PCOS. Hyperinsulinemia (serum insulin >15 μlU/mL) was present among 19.2% of diagnosed PCOS cases. Conclusion: The study demonstrates that PCOS is an emerging disorder during adolescence and screening could provide opportunity to target the group for promoting healthy lifestyles and early interventions to prevent future morbidities