UTILIZATION AND EVALUATION OF SELECTIVE SEROTONIN REUPTAKE INHIBITORS(SSRI's) IN PSYCHIATRY PATIENTS OF SECONDARY CARE TEACHING HOSPITAL OF SOUTH INDIA

Abstract

Selective serotonin reuptake inhibitors (SSRI's) are the most commonly prescribed antidepressants. They are mainly prescribed to treat depression. SSRI's are considered to be safer and generally cost effective when compared to some newer antidepressant classes. SSRI's acts by inhibiting the serotonin transporter (SERT) at the presynaptic axon terminal. A number of factors must be considered when evaluating SSRI's. An SSRI drug utilization study is performed for further evaluation. The study was a prospective obs Methodology: ervational study on “Utilization and Evaluation of SSRI's in Psychiatry Patients”, which was carried out in the 'Department of Psychiatry' in a Secondary care teaching hospital of South India. Study the maximum number of patients was 786 and the age groups of 981 out of which m Results: aximum were of age group 46-54 and minimum were above 60, the female were more suffered in that maximum were married and the educational levels of the patients were mostly secondary, the hygienic conditions, surroundings and cleanliness were good. Discussion: Recent studies also found that mostly used SSRIs are Fluoxetine, Paroxetine, Citalopram and Sertraline. We found that in our hospitals the data reveals the status for some mostly used Fluoxetine as 386 (49.10%) and Paroxetine 288 (36.64%). Conclusion: Our study concluded that most of the patients suffered with psychological conditions and symptoms are considered. After using SSRI their overall effect in the patient health and outcome was observed with better outcome.