TO STUDY THE PREVALENCE OF METABOLIC SYNDROME AND LIFESTYLE FACTORS IN SUBFERTILE MALES IN CENTRAL INDIA

Abstract

Background: Male partner constitute the 50% of couple infertility, among which the abnormal semen quality is the most common cause. There are many factors that can affect sperm quality including metabolic syndrome and modiable lifestyle factors. Previous literatures regarding effects of metabolic syndrome (MetS) and lifestyle factors on semen quality is inconsistent. So, we decided to nd the prevalence of metabolic syndrome and life style factors in subfertile low sperm counts males and improvement in semen quality after treating deranged metabolic parameters and lifestyles modication. Methods: 51 male partners of infertile couple with low normal sperm count included in this study. MetS was dened by the modied NCEP ATP III criteria with the Asian cut-off for waist circumference. Life style modiable factors are assessed by using a questionnaire. All patients underwent lifestyle modication for a period of 3 months. The association of metabolic syndrome and lifestyle factors with semen analysis was examined and the changes in semen parameters after life style modication was evaluated. Results: Metabolic syndrome was signicantly associated with reduced sperm count and motility. In life style factors, the sperm count with physical activity grades was found to be statistically signicant (P=0.002). Sperm motility was negatively associated with stress level, depression level, smoking grades and Homocysteine level. After 3 months of life style modications, there was signicant increase in sperm count and sperm motility. Conclusions: Acquiring a healthy life style lead to improvement in sperm count and motility and may consequentially reduce the infertility risk in couples. Physician should strongly advise their patients to adopt a healthy life style including daily physical activity and exercise, reduce obesity, to cut out stress and avoid smoking before undergoing medical treatment.