A NEW INSIGHT ON MICROBIAL ENDOPHYTES

Abstract

Plants existed on earth, ages before man. Obviously ailing humans restored plants’cure since very very ancient times. Plants produce phytochemicals which are used for the treatment of various diseases including Urolithiasis. But in recent years a new trend in treatment is introduced, as it is discovered that many vital activities of the host plant are known to be inuenced by the presence of microorganisms. These micro-organisms are referred as Endophytes.Some of these Endophytes produce Oxalate oxidase, a necessary enzyme for degradation of Calcium Oxalate. Several researches also concluded the presence of oxalate degrading bacteria in human intestine and humans lack the ability to produce oxalate degrading enzymes. Based on this concept, it can be considered that intestinal micro ora may have potential to degrade urine stone, i.e. calcium oxalate crystals by inuencing absorption of dietary oxalate. Hence, retention of this microbiota using probiotics maybe useful in prevention and treatment of urolithiasis.