FUNCTIONING PITUITARY TUMOURS: A CLINICOBIOCHEMICAL CORRELATION

Author:

Chakraborty Parna1,Datta Parthasarathi2

Affiliation:

1. Senior Resident, Department Of Biochemistry, College Of Medicine And Sagore Dutta Hospital, Kolkata, Westbengal, India.

2. Associate Professor, Department of Neurosurgery, NRS Medical College, Kolkata, Westbengal, India.

Abstract

Introduction Pituitary tumours may be functioning or non-functioning. Functioning tumours secrete PRL, GH, ACTH, TSH, FSH, LH and have clinical features pertaining to the hormones. We in our study tried to analyze the pre-op and post-op clinicoendocrinological( biochemical) status. Materials and methods Over a span of 10 years from Jan 2010 to Jan 2020 we studied the pre-op and post-op clinical features, radiology (CT, MRI) and endocrine levels of 20 patients with functioning pituitary adenomas. Results Completeness of tumour removal dictates normalization of clinical features and endocrine levels. Microadenomas pose a more remission rate than macroadenomas. Conclusion Total tumour removal in a functioning pituitary adenoma normalizes the clinicoendocrinological parameters. Normalization rates are far more for microadenomas than macroadenomas.

Publisher

World Wide Journals

Reference9 articles.

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