Affiliation:
1. Reader Omdr / Deshbhagat Dental College Mandigobindgarh Punjab.
2. Reader Oral Pathology / Deshbhagat Dental College Mandigobindgarh Punjab.
3. Prof & Head /Community Dentistry/ Deshbhagat Dental College Mandigo bindgarh Punjab
Abstract
Oral submucous brosis is a common pre-malignant condition affecting the oral mucosa with more
prevalence among Indian population. Various treatment modalities have been elucidated in order to
alleviate the symptoms associated with OSMF.
Currently oral Anti hypertensive has been proved to have benecial result in treating OSMF because of its anti-inammatory,
brinolytic, immunomodulatory and rheologic modifying property.
Several categories of drugs have been used in the treatment of OSMF but their effectiveness leaves much to be desired and no
treatment regimen has afforded denitive cure. While Oral administration limits the concentration of drugs in lesional tissue
and increases the potential for side effects, the Intralesional injections are associated with signicant mechanical injury and
non compliance on the patient’s part because of the accompanying discomfort and pain.
The present study was done to evaluate the effectiveness of oral antihypertensives in the management of OSMF
Very few studies across world have showed that anti hypertensive drugs showed signicant improvement in mouth opening,
reduction in burning sensation.
Hence anti hypertensive can be a good alternative in the management of OSMF for whom intralesional steroids or
hyaluronidase are contraindicated, for those who cannot make frequent visit and to avoid pain due to injection. And most
importantly anti hypertensive is cost effective and more compliant to the patient.