CLINICO- HISTOPATHOLOGICAL CORRELATION IN WOMEN WITH POST MENOPAUSAL BLEEDING – A CROSS SECTIONAL ANALYSIS

Abstract

Objective: This study aims to evaluate women with post-menopausal bleeding by corelating the clinical data with endometrial pathology by endometrial sampling and to discover risk variables linked to the development of endometrial cancer in the future. For this study we retrospectively studied 48 women with postmenopausal bleeding who had undergoneMethods: endometrial sampling. Their case record was obtained from the medical record department. Their detailed history, examination ndings and reports of their investigation were collected from their case records. The same was analysed to seek correlation between clinical and histopathological examination features In this study the mean age of women presented with postmenopausal bleeding was 54.94 andResults: mean duration of menopause was 7.52 years. The mean endometrial thickness was 10.19mm. The histopathological analysis showed disordered proliferation (33%), irregular shedding (16.7 %), endometrial polyp (10.4%) and Enometrial atrophy (4.2%). Endometrial carcinoma like endometroid Ca (2.1%) and pleomorphic sarcoma (2.1%) were observed. The subjects also had cervical pathologies such as cervical erosion (10.4%), chronic papillary cervicitis (8.3%) and 3(6.3%) patients had squamous metaplasia of cervix Even though mostConclusion: occurrences of postmenopausal bleeding have benign causes, it is important to rule out premalignant and malignant endometrial lesions while analysing these cases. Postmenopausal bleeding can therefore be a sign of several etiologies other than cancer. Due to this, rigorous histologic study is necessary to distinguish between benign and malignant.