HYPOCHLOROUS ION BASED DRESSING: THROWBACK TO THE SURGEONS’ CHOICE
Author:
G Manikantha1, Jawale Hemant Muktaram1, Kumar Mishra Akshat Awdhesh1, Tandur Amarjeet E2, Agrawal Pratik J3
Affiliation:
1. MBBS, Junior Resident, Department of General Surgery, Grant Government medical college, Sir JJ group of hospitals, Mumbai, India. 2. MS, Assistant Professor, Department of General Surgery, Grant Government medical college, Sir JJ group of hospitals, Mumbai, India 3. MBBS, Department of General Surgery, Government medical college and hospital Aurangabad
Abstract
1.1 BACKGROUND : As per Robbin's pathology(Robbins & Cotran Pathologic Basis of Disease - 10th
Edition, n.d.) "an ulcer is the breach of the continuity of skin, epithelium or mucous membrane caused by
sloughing out of inamed necrotic tissue." In an era of modern-day fast track surgery and premier practices of medicine,
management of wound remains an archaic, almost omnipresent challenge to a health care provider mediating the need for
solutions. The hunt for an optimum dressing agent has been everlasting, one of which is our point of discussion in this study.
The addition of Chlorine(Cl2) to Water(H2O) gives rise to Hypochlorous ion, a weak acid that has been used traditionally as
disinfectant, sterilizer and beaches. These properties can be utilised for wound disinfection and swifter wound healing.
1.2 AIMS AND OBJECTIVES:
Ÿ To study the efcacy of Hypochlorous ion-based dressing over traditional normal saline based dressing .
Ÿ To study the effects factoring in various associated comorbidities
in patients such as Diabetes Mellitus, Peripheral Vascular Disease, Trauma and
Pressure Ulcer.
1.3 METHODOLOGY: A comparative study was conducted in a tertiary care facility in India that included 101 patients who were
distributed randomly utilizing computerised algorithms into study and control group. The control group received daily normal
saline dressing whereas the study group underwent daily hypochlorous ion-based dressing. The subjects were analysed after 4
weeks and evaluated for decrease in wound surface area and improvement of wound quality and tabulated for analysis.
1.4 CONCLUSION: Hypochlorous ion based daily dressing shows signicant reduction in wound surface area as well as
signicantly better and faster improvement in the quality of wound in patients of Traumatic, Diabetic and Pressure Ulcer
whereas the results in patients suffering from Peripheral Vascular Disease were equivocal.
Publisher
World Wide Journals
Reference16 articles.
1. Robins and Cotran’s Pathologic Basis of Disease. Textbook by Abul K. Abbas, Jon C Aster, MD PhD, Stanley L Robbins, and Vinay Kumar 2. Five Millennia of Wound Care Products — What is New? A Literature Review. Chantal M. Mouës, MD; Freerk Heule, MD, PhD; Ron Legerstee, RN, MSc; and Steven E.R. Hovius, MD, PhD 3. A HANDBOOK OF ANTISEPTICS BY HENRY DRYSDALE DAKIN, D.Sc., F.I.C., F.R.S. AND EDWARD KELLOGG DUNHAM, M.D.EMERITUS PROFESSOR OF PATHOLOGY, UNIVERSITY AND BELLEVUE HOSPITAL MEDICAL COLLEGE MAJOR, MEDICAL OFFICERS RESERVE CORPS, U. S. ARMY 4. Hypochlorous Acid: An Ideal Wound Care Agent With Powerful Microbicidal, Antibiofilm, and Wound Healing Potency. Serhan Sakarya, Necati Gunay, Meltem Karakulak, Barcin Ozturk, Bulent Ertugrul 5. Bactericidal and wound-healing properties of sodium hypochlorite solutions: the 1991 Lindberg Award. Heggers JP1, Sazy JA, Stenberg BD, Strock LL, McCauley RL, Herndon DN, Robson MC.
|
|