Abstract
Background: The purpose of study is to evaluate clinical profile of children with hemolytic anemia with necessary investigation along with growth parameters of these children with reference to anemia and parental awareness to recognize the degree of pallor in their affected children.
Methods: The study was carried out in patients of Krishna hospital and Medical research centre,Karad in period of January 2018 to august 2018 .A total of 36 cases were included in the study.Children aged between 4 months to 12 years diagnosed to have hemolytic anemia, those who had given consent, those who came to our hospital
for blood transfusion were included in study.
Results: Among the study, sickle cell disease ,sickle beta thalassemia and sickle beta thalassemia trait are present in majority of the patients (61.09%). Beta thalassemia major along with beta thalassemia intermedia is present in 38.88% of the cases.
Conclusion:Sickle beta thalassemia and sickle cell disease forms the major types of hemolytic anemia .Parental awareness of presence of paleness and anemia is poor. No relation to religion , social group and consanguinity .
Reference17 articles.
1. Kliegman RM, Behrman RE, Jenson HB, Stanton BF. Nelson Text book of paediatrics. 19th edn. New Delhi: Elsevier saunders; 2013 p.1659- 1683.
2. Philip Lanzkowsky, Manual of Pediatric Hematology and Oncology. 4th edition. United states of America: Elsevier Academic Press; 2005. P.136-198
3. Weatherall DJ. Clegg TB. Higgs DR, Wood WG the hemoglobinpathies In: Scriver CR, Beaudet AL, Sly WS, Valle D (Eds), The Metabolic and Molecular Bases of Inherited Diseases,8th edition, New York: McGrawHill;2001. 4571-4636
4. Angastinosis M, Modell B. Global epidemiology of hemoglobin disorders. Proc Natl Acad Sci USA 1998;850:251
5. UNICEF. The state of the world’s children. Oxford: Oxford University Press, 1996;250