CORONAVIRUSES AND POTENTIAL VACCINES

Abstract

It is believed that CoVs might have been transmitted to humans via animals. Those causing SARS, MERS and COVID-19 probably have originated from bats. Possibly the transfer of the new CoV strain from the original host species to humans must have involved another animal species which acted as an intermediate host. The SARS-CoV-2, is most closely related to a group of SARS-CoVs found in humans, bats, pangolins and civets. As the virus was new, it potentially infected very large numbers of people all around the globe and thus resulted into pandemic. Even though the number of very severe cases was low in terms of percentage but taking it into terms of number it becomes a very large count of people with acute illness. SARS-CoV-2 infected patients reportedly develop low titre neutralizing antibody and usually suffered prolonged illness, that showed a more effective SARS-CoV-2 immune surveillance evasion when compared with SARS-CoV. Various treatments were tried and different vaccines were tested out to ght against this deadly virus all around the globe. In this article , a brief review of information on different CoVs and its various vaccine has been made.