A COMPARATIVE STUDY OF SAFETY & EFFICACY OF ORAL MISOPROSTOL VERSUS OXYTOCIN IN PREVENTION OF POSTPARTUM HAEMORRHAGE

Author:

Maurya Dipali1,Sharma Anju2,Agrawal Megha3

Affiliation:

1. 3 Year Resident , SMS MC Jaipur

2. Unit Head And Senior Professor , SMS MC Jaipur

3. Associate Professor , SMS MC Jaipur

Abstract

OBJECTIVE: To compare oral misoprostol with intramuscular oxytocin in prevention of postpartum haemorrhage in low risk vaginal birth in a tertiary care centre. METHOD: In a prospective , open label controlled trial, 60 women were randomly allocated to 2 groups. Gr A – 10 units oxytocin i.m Gr B - 600µg misoprostol orally within 1 minute of delivery. The outcome measured was blood loss within 1 hour and 24hrs of delivery. RESULTS: The mean blood loss in 1 hour post delivery was 151.14 ±12.40ml in Group A and 149.82±10.36 ml in Group B. The mean blood loss within 24hrs after delivery was 218.59 ±33.63 ml in Group A and 230.11±31.82 ml in Group B. There was no signicant difference between the groups in terms of blood loss within1 hr and 24 hrs of delivery. CONCLUSION: oral misoprostol 600μg is as effective as intramuscular oxytocin 10IU in the prevention of PPH in low risk vaginal delivery.

Publisher

World Wide Journals

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