EFFICACY OF STEROID AND PROTON PUMP INHIBITORS IN PATIENTS UNDERGOING TONSILLECTOMY - A COMPARATIVE STUDY

Abstract

INTRODUCTION: All tonsillectomy techniques share the same characteristics of producing an avulsion wound exposing the underlying tissues which requires extensive healing by secondary intention. our study aims to compare two pharmacological agents and analyze their clinical outcome in post operative recovery of tonsillectomy patients. MATERIALS AND METHODS: Patients were randomly divided into two groups- Group A and Group B. Group A received Injection Dexamathasone, while group B received oral pantoprazole. Post operatively patients were assessed for post operative pain, wound healing and incidence of secondary hemorrhage on Post operative Day (POD) 0, 1, 7, 14. RESULTS: Group A (steroid) had comparatively less pain on POD 0 and POD 1. However there was no significant differnence between both the groups on POD 7 and 14. Incidence of secondary haemorrhage was seen in Group A (2%), but no incidence of haemorrhage was recorded in Group B. Both the groups did not show statistically significant difference in regards to wound healing. DISCUSSION: Tonsillectomy as a surgical procedure has evolved over the years. Our study took into account two pharmacological agents, dexamethasone and pantoprazole which act by different mechanism and measured their clinical outcomes in managing post tonsillectomy patients. CONCLUSION: The study concluded that there was no significant statistical difference between the two drugs in alleviating postoperative pain, wound healing and secondary haemorrhage.