Affiliation:
1. IZMIR UNIVERSITY OF ECONOMICS, SCHOOL OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE
2. İZMİR EKONOMİ ÜNİVERSİTESİ, TIP FAKÜLTESİ
Abstract
Aim: Subacute thyroiditis (SAT) is a thyroid disease that seriously affects the quality of life for patients
caused by acute inflammation of the thyroid gland. Apart from classical acute phase reactants, the values
and rates obtained from peripheral blood count (mean platelet volume (MPV), neutrophil-to-lymphocyte
ratio (NLR), and platelet-to-lymphocyte ratio (PLR)) values are also accepted as practical indicators
of systemic inflammation. Our aim in this study is to compare the effects of systemic inflammation
markers and the treatments given in the laboratory tests of our patients with a diagnosis of SAT, on the
hypothyroid state one year later.
Material and Methods: In this study, which was carried out with a retrospective method, 133 patients
were included in the study. The medical data of these patients at the time of SAT diagnosis and one
year later were analyzed. 37 patients were in the steroid group and 97 patients were in the nonsteroidal
anti-inflammatory drug (NSAID) group.
Results: The male/female ratio was similar in both groups. Female dominance was observed in both
groups in patients diagnosed with SAT. The thyroid tests of the groups, which were hyperthyroid at the
beginning and euthyroid one year later, were similar between the groups (p>0.05). Both groups had
an increase in acute phase reactants at baseline (erythrocyte sedimentation rate [ESR] and C-reactive
protein (CRP) levels) and normalized after treatment. Neutrophil (p0.05) and
platelet (p0.05).
Conclusion: Inflammation markers and treatments applied in SAT patients did not have a significant
effect on the prognosis
Publisher
Bulent Evcevit University
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