Effect of Socioeconomic Status on Mortality Among People With Type 2 Diabetes

Author:

Walker Jeremy J.1,Livingstone Shona J.2,Colhoun Helen M.2,Lindsay Robert S.3,McKnight John A.4,Morris Andrew D.2,Petrie John R.5,Philip Sam6,Sattar Naveed3,Wild Sarah H.1,

Affiliation:

1. Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland

2. Biomedical Research Institute, University of Dundee, Dundee, Scotland

3. British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland

4. Metabolic Unit, Western General Hospital, Edinburgh, Scotland

5. Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, Scotland

6. School of Medical Sciences, University of Aberdeen, Aberdeen, Scotland

Abstract

OBJECTIVE The study objective was to describe the effect of socioeconomic status (SES) on mortality among people with type 2 diabetes. RESEARCH DESIGN AND METHODS We used a population-based national electronic diabetes database for 35- to 84-year-olds in Scotland for 2001–2007 linked to mortality records. SES was derived from an area-based measure with Q5 and Q1 representing the most deprived and affluent quintiles, respectively. Poisson regression was used to estimate relative risks (RRs) for mortality among people with type 2 diabetes compared with the population without diabetes stratified by age (35–64 and 65–84 years), sex, duration of diabetes (<2 and ≥2 years), and SES. RESULTS Complete data were available for 210,994 eligible individuals (99.4%), and there were 33,842 deaths. Absolute mortality from all causes among people with type 2 diabetes increased with increasing age and socioeconomic deprivation and was higher for men than women. RR for mortality associated with type 2 diabetes was highest for women aged 35–64 years in Q1 with diabetes duration <2 years at 4.83 (95% CI 3.15–7.40) and lowest for men aged 65–84 years in Q5 with diabetes duration ≥2 years at 1.13 (1.03–1.24). CONCLUSIONS SES modifies the association between type 2 diabetes and mortality so that RR for mortality is lower among more deprived populations. Age, sex, and duration of diabetes also interact with type 2 diabetes to influence RR of mortality. Differences in prevalence of comorbidities may explain these findings.

Publisher

American Diabetes Association

Subject

Advanced and Specialized Nursing,Endocrinology, Diabetes and Metabolism,Internal Medicine

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