1. Sunnybrook Health Sciences Centre Research Institute, Departments of Medicine and Immunology, University of Toronto, Toronto, Ontario, Canada; the
2. Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, Ontario, Canada; the
3. Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, Tennessee; the
4. Department of Laboratory Medicine and Pathology, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; and the
5. Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.