Loss of Pulsatile Insulin Secretion: A Factor in the Pathogenesis of Type 2 Diabetes?
Author:
Affiliation:
1. Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
2. Cebix AB, Karolinska Institutet Science Park, Solna, Sweden
Publisher
American Diabetes Association
Subject
Endocrinology, Diabetes and Metabolism,Internal Medicine
Link
https://journals.org/diabetes/diabetes/article-pdf/61/9/2228/559692/2228.pdf
Reference16 articles.
1. Mechanisms for insulin resistance: common threads and missing links;Samuel;Cell,2012
2. Targeting beta-cell function early in the course of therapy for type 2 diabetes mellitus;Leahy;J Clin Endocrinol Metab,2010
3. Pulsatile insulin secretion accounts for 70% of total insulin secretion during fasting;Pørksen;Am J Physiol,1995
4. Glucose generates coincident insulin and somatostatin pulses and antisynchronous glucagon pulses from human pancreatic islets;Hellman;Endocrinology,2009
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